Why is it so hard to lose the weight? Secrets of weight gain revealed in a radio interview


Dr Prab R Tumpati, MD Founder of W8MD Medical Weight Loss Centers Of America

Why it’s so hard to lose weight and what you can do about it? 

Secrets of weight gain revealed!

in a Health Watch Radio Interview by Dr. Prab R. Tumpati, MD – founder of W8MD Medical Weight Loss Centers of America!

During the past 20 years, there has been a dramatic increase in obesity in the United States and rates remain high. More than one-third of U.S. adults (35.7%) and approximately 17% (or 12.5 million) of children and adolescents aged 2—19 years are obese. Also, another 33% of all adults are in the overweight category.

What do you think is contributing to this?

There are many factors that contribute to weight gain but I think there about 3 things that I see as important.
Hippocrates, father of medicine said “Let Food Be Your Medicine, Medicine Be Your Food”
As we moved away from this concept, and see food merely as “calories in, calories out”, we run in to issues such as obesity.

Here are three things that happened to the modern diet that contribute to the high levels of inflammation that we currently see in the population at large leading to increased disease burden. Understanding these three fundamental principles forms the foundation for a healthy and long life with reduced inflammation level in the body.

What is the most important factor that leads to weight gain in your opinion?

First, insulin resistance or metabolic syndrome, that affects one in three Americans and leads to belly fat accumulation. Unlike the subcutaneous fat which is protective, studies have shown that belly fat produces cytokines and other inflammation causing chemicals leading to increased risk of cardiovascular disease, diabetes and other conditions. In fact, waist circumference of over 40 inches in men and 36 inches in women(lower in Asian Populations), is one of the five criteria for metabolic syndrome.

Does inflammation play a role in weight gain?

The lack of polyphenols and other antioxidants in the diet is a second factor. Before the modern food processing era, our diet used to have more than 50 percent unprocessed and uncooked food items such as colored fruits, vegetables, and other natural ingredients that are high in antioxidants such as polyphenols. Studies have shown that lack of polyphenols leads to increased inflammation in the body.

How does Omega 3 fatty acids fit in to this?

Third, the ratio of Omega 3 to Omega 6 fatty acids used to be 1:1 but is now at 1:16 which also increases inflammation.

With the above 3 factors, the inflammation levels rise significantly thereby increasing the risk of many health problems including cardiovascular diseases, diabetes and even increased risk of certain types of cancers! in this context, it is important to remember that most human diseases start with inflammation!

This interview of Dr Prab R Tumpati MD, founder of W8MD Medical Weight Loss Centers of America will be aired on Monday, July 22nd at 8:00 PM EST on Health Watch Radio 97.5 FM and is available on the link below for online listeners.


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  1. Pingback: Losing weight in New York City | W8MD's New York City Insurance Weight Loss

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