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Bupropion is a medication that is commonly used for the treatment of depression, seasonal affective disorder, and smoking cessation. It is sold under the brand names Wellbutrin, Zyban, and Aplenzin. Bupropion works by increasing the levels of norepinephrine and dopamine in the brain. This article will explore the uses, dosages, side effects, and precautions associated with Bupropion.


Bupropion is primarily used to treat depression. It is effective in treating both major depressive disorder and seasonal affective disorder. Bupropion is also used as a smoking cessation aid. It reduces cravings and withdrawal symptoms associated with nicotine addiction. Additionally, Bupropion may be used off-label to treat attention deficit hyperactivity disorder (ADHD) and bipolar disorder.

Bupropion molecule ball


The dose of Bupropion varies depending on the condition being treated. For depression, the starting dose is typically 150mg once daily. The dose may be increased to a maximum of 300mg per day. For smoking cessation, the starting dose is also 150mg per day, but the medication is usually taken for a shorter duration. The maximum recommended duration of treatment for smoking cessation is 12 weeks. If Bupropion is being used to treat ADHD, the dose may be higher, up to 450mg per day.

Side Effects

Common side effects of Bupropion include dry mouth, headache, nausea, and insomnia. Less common side effects include seizures, tremors, and confusion. If you experience any of these less common side effects, seek medical attention immediately. Bupropion may also increase the risk of suicidal thoughts or actions, especially in young adults. This risk is highest during the first few weeks of treatment.


Bupropion should not be taken if you have a history of seizures or an eating disorder. It should also be used with caution in patients with liver or kidney disease. If you are taking other medications, be sure to discuss them with your doctor before starting Bupropion, as it may interact with certain drugs. Bupropion should not be taken during pregnancy or while breastfeeding.

Also see

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