Korsakoff syndrome
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(ks) is an amnestic disorder caused by thiamine (vitamin b1) deficiency typically associated with prolonged use of alcohol. The syndrome and psychosis are named after sergei korsakoff, the russian neuropsychiatrist who discovered it during the late 19th century. This neurological disorder is caused by a lack of thiamine in the brain, and is also exacerbated by the neurotoxic effects of alcohol. When wernicke encephalopathy accompanies korsakoff syndrome the combination is called wernicke–korsakoff syndrome; however, a recognized episode of wernicke encephalopathy is not always obvious.
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