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Created page with "Setmelanotide is a medication that has recently been approved for the treatment of obesity caused by certain genetic conditions. It is a melanocortin-4 receptor agonist that helps to regulate hunger and satiety signals, which can lead to weight loss in patients with specific genetic mutations. ==FDA approval== Setmelanotide was approved by the US Food and Drug Administration (FDA) in November 2020 for the treatment of obesity caused by proopiomelanocortin (POMC) deficien..."