Hormonal causes of weight gain

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Insulin resistance is a condition that can lead to weight gain and difficulty losing weight. It occurs when the body's cells become less responsive to insulin, a hormone that regulates blood sugar levels. As a result, the pancreas produces more insulin to compensate, which can lead to high levels of insulin in the bloodstream. This can cause the body to store more fat and make it difficult to burn stored fat for energy.

Metabolic conditions

Insulin resistance is often associated with other metabolic conditions, such as metabolic syndrome, type 2 diabetes, obesity, and high blood pressure. It can also lead to a condition known as metabolic syndrome, which is a cluster of health issues that increase the risk of heart disease, stroke, and other chronic health conditions.


There are several factors that can contribute to insulin resistance, including a diet high in processed and sugary foods, lack of exercise, and genetics. Treatment for insulin resistance typically involves lifestyle changes, such as adopting a healthy diet and increasing physical activity. In some cases, medication may also be prescribed to help regulate blood sugar levels and improve insulin sensitivity.

Other hormonal factors

Other hormonal causes of weight gain include thyroid disorders, such as hypothyroidism, and imbalances in cortisol, a hormone produced by the adrenal glands in response to stress. These conditions can also lead to difficulty losing weight and may require medical treatment, such as thyroid hormone replacement therapy or stress management techniques.

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